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  1. An opponent or enemy.
  2. One who antagonizes or stirs.
  3. (biochemistry) A chemical that binds to a receptor but does not produce a physiological response, blocking the action of agonist chemicals.
    • 2001: The calcium antagonists represent one of the top ten classes of prescription drugs in terms of commercial value, with worldwide sales of nearly $10 billion in 1999. " Leslie Iversen, Drugs: A Very Short Introduction (Oxford 2001, p. 41)
    Etymology: From (term, antagonista, lang=la), from Ancient Greek (term, sc=polytonic, á, , opponent, lang=grc), from (term, sc=polytonic, á, , antagonize, lang=grc).

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